Why the study?
What are the rates, characteristics, and appropriateness of ICD therapies delivered to patients with sustained VT or VF?
Population
449 patients with documented sustained ventricular tachycardia or ventricular fibrillation randomized to ICD…
Design
Cohort
Follow-up
2 years
Authors
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Frequent therapies in secondary prevention warrant optimized programming; leaves open shocks as valid mortality surrogates in trials.
What are the rates, characteristics, and appropriateness of ICD therapies delivered to patients with sustained VT or VF?
ICD therapies are frequently delivered in secondary prevention patients, primarily for VT, but high rates of inappropriate therapy indicate that ICD shocks should not be used as a surrogate endpoint for mortality in clinical trials.
Klein et al. (2003) studied this question.
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