Key result
Participation in cardiac rehabilitation among adults recently hospitalized with heart failure improved the mean frailty index by 0.03 units at 6 months (95% CI 0.02-0.04; P<0.001).
Why the study?
Frailty is common in heart failure and associated with poorer outcomes, but characteristics, exercise participation, and outcomes of frail versus not-frail participants in cardiac rehabilitation exercise training required description.
Does exercise training improve frailty and physical activity in frail patients recently hospitalized with heart failure?
Population
256 adults recently hospitalized with HF
Comparison
Frail and very frail vs not-frail participants, and center-based ET vs home exercise alone
Design
Secondary analysis of a randomized trial
Follow-up
12 months
Authors
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Supports offering CR exercise to frail HF patients; leaves open any impact on death or readmission.
RCT (n=256)
randomized
Yes
Does exercise training improve frailty and physical activity in frail patients recently hospitalized with heart failure?
Mean Difference: 0.03 (95% CI 0.02–0.04)
p-value: p=<0.001
Frail patients with heart failure participating in cardiac rehabilitation can achieve physical activity guidelines and experience meaningful reductions in frailty.
Mudge et al. (2021) conducted an RCT in Heart failure (n=256). Center-based exercise training vs. Home exercise prescription and monitoring was evaluated on Change in frailty index at 6 months (Mean improvement 0.03, 95% CI 0.02-0.04, p=<0.001). Participation in cardiac rehabilitation among adults recently hospitalized with heart failure improved the mean frailty index by 0.03 units at 6 months (95% CI 0.02-0.04; P<0.001).
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