Key result
Transcatheter Aortic Valve Implantation (TAVI) resulted in an overall vascular complication rate of 10.44%, with significant correlations to coronary artery disease, valve type, and access point.
Why the study?
Despite clinical success with TAVI for aortic stenosis, the incidence and implications of vascular complications remain a subject of critical concern.
Cohort (n=1,343)
Vascular complications occur in approximately 10% of TAVI procedures, are significantly associated with CAD, valve type, and access point, and lead to extended hospitalization.
Vascular injury still lengthens TAVI stays; leaves open whether CAD, valve type or access independently drive events.
OBJECTIVE: Transcatheter Aortic Valve Implantation (TAVI) has emerged as a pivotal therapeutic modality for aortic stenosis, predominantly in the elderly population. Despite its clinical success, the incidence and implications of vascular complications during TAVI remain a subject of critical concern. METHODS: A retrospective analysis was conducted on 140 patients who experienced vascular complications during TAVI procedures from a total cohort of 1343 cases. Patient demographics, clinical profiles, and procedural characteristics were scrupulously examined. Vascular complications, both intraoperative and postoperative, were identified through various diagnostic modalities. Statistical analyses were employed to discern associations and significance levels. Comparative assessments with international literature were performed to gain broader insights. RESULTS: The study unveiled an overall incidence of vascular complications at approximately 10.44%. Coronary Artery Disease (CAD)-p-value (0.013), choice of valve type-p-value (0.016), and access point-p-value (0.027) demonstrated significant correlations with these complications. Complication incidences in TAVI procedures included pseudoaneurysms (4.76%), arteriovenous fistulas (1.49%), hematomas (0.37%), dissections (2.24%), arterial perforations (0.15%), stenosis/occlusion (0.37%), and closure device failures (1.94%). Over 70% of complications at the valve entry point result from dissections and closure device failures, while the pigtail entry point is predominantly linked to over 70% of pseudoaneurysms. Extended hospitalization (7.84 ± SD 3.14) was observed for patients experiencing vascular complications, underlining the importance of vigilant postprocedural care. CONCLUSION: This study provides comprehensive insights into vascular complications during TAVI procedures, shedding light on their incidence, risk factors, clinical presentations, diagnostic methodologies, and management strategies.
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Cheilas et al. (2024) conducted a cohort in Aortic stenosis (n=1,343). Transcatheter Aortic Valve Implantation (TAVI) was evaluated on Vascular complications. Transcatheter Aortic Valve Implantation (TAVI) resulted in an overall vascular complication rate of 10.44%, with significant correlations to coronary artery disease, valve type, and access point.
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