Why the study?
Does single isometric knee extension produce rapid-onset vasodilation in the human leg compared to the forearm?
Population
16 healthy men
Comparison
Single isometric knee extension contractions at… vs Single isometric contractions of the forearm
Design
Other, random ordered single contractions
Authors
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Legs may model rapid-onset vasodilation studies; leaves open translation to clinical vascular assessment in patients.
Does single isometric knee extension produce rapid-onset vasodilation in the human leg compared to the forearm?
Single muscle contractions in the human leg produce rapid and robust vasodilation that is largely independent of mechanical factors, establishing the leg as a viable model to study rapid-onset vasodilation.
Credeur et al. (2014) studied this question.
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