Key result
Visceral adiposity explained the majority of the variance in liver fat (p<0.0001) and mediated the inverse relationship between cardiorespiratory fitness and liver fat in both sexes.
Why the study?
Whether the association between liver fat and cardiorespiratory fitness is mediated by visceral adiposity was unknown.
Does visceral adiposity mediate the relationship between cardiorespiratory fitness and liver fat in asymptomatic adults?
Population
320 asymptomatic participants (43% women)
Comparison
Associations across sex-specific tertiles of liver fat and cardiorespiratory fitness
Design
Cross-sectional study
Authors
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VAT mediation should not yet change fitness counseling for liver fat; leaves open whether CRF cuts LF independently of VAT.
Cross-Sectional (n=320)
Does visceral adiposity mediate the relationship between cardiorespiratory fitness and liver fat in asymptomatic adults?
p-value: p=<0.0001
Visceral adiposity is an important mediator in the inverse relationship between cardiorespiratory fitness and liver fat in asymptomatic adults.
Chartrand et al. (2025) conducted a cross-sectional in Asymptomatic adults (n=320). Cardiorespiratory fitness was evaluated on Mediation of the relationship between cardiorespiratory fitness and liver fat by visceral adipose tissue (p=<0.0001). Visceral adiposity explained the majority of the variance in liver fat (p<0.0001) and mediated the inverse relationship between cardiorespiratory fitness and liver fat in both sexes.
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