Why the study?
Does moderate-intensity exercise training delay the progression of hypertension and improve cardiac function in young spontaneously hypertensive rats?
Population
Young normotensive (Wistar-Kyoto) and spontaneously hypertensive rats (SHRs)
Comparison
Moderate-intensity exercise training for 16 weeks vs Sedentary control
Design
Preclinical
Follow-up
16 weeks
Authors
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Should not alter hypertension management; leaves open translation of rat exercise benefits to clinical practice.
Does moderate-intensity exercise training delay the progression of hypertension and improve cardiac function in young spontaneously hypertensive rats?
Chronic exercise training delays hypertension progression and improves cardiac function in spontaneously hypertensive rats by reducing proinflammatory cytokines and improving redox homeostasis via NF-kB downregulation.
Agarwal et al. (2009) studied this question.
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