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a major role in the pathogenesis of many diseases. Cancer is one of this diseases. The balance is disrupted between of cell proliferation and cell death in cancer and cells fail to receive the death signals to perform apopitosis. This may cause problems in any step of the apopitotic pathways. apopitotic mechanisms and defects that may occur in these mechanisms and the relationship with carcinogenesis of these defects are given place in this review.
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Bildik et al. (2018) studied this question.
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