Key result
Intensive blood pressure control to below 130/80 mmHg in patients with chronic kidney disease reduces future mortality risk, outweighing the potential risks of early, reversible declines in renal function.
Why the study?
Recent ACC/AHA guidelines recommended intensive blood pressure targets for CKD based on SPRINT, but renal outcomes were concerning and other guidelines retained traditional definitions.
Does intensive blood pressure control improve renal and mortality outcomes in patients with chronic kidney disease?
Does intensive blood pressure control improve renal and mortality outcomes in patients with chronic kidney disease?
Intensive blood pressure control (<130/80 mmHg) in CKD patients, as recommended by the 2017 ACC/AHA guidelines, offers mortality benefits despite an increased risk of mostly reversible acute kidney injury.
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Hong Sang Choi (2019) conducted a review in Hypertension in Chronic Kidney Disease. Intensive blood pressure control vs. Standard blood pressure control was evaluated. Intensive blood pressure control to below 130/80 mmHg in patients with chronic kidney disease reduces future mortality risk, outweighing the potential risks of early, reversible declines in renal function.
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