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September 1, 1997Journal of Interferon & Cytokine Research

The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function

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Authors

MCMichael J. ClemensSt George's HospitalAEAndroulla EliaSt George's, University of London

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Clemens et al. (1997) studied this question.

synapsesocial.com/papers/6a7f14740d396ca0cf0fc545https://doi.org/10.1089/jir.1997.17.503
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin.1996 · 101 citations
  2. 2Activation of interferon-regulated, dsRNA-dependent enzymes by human immunodeficiency virus-1 leader RNA1989 · 132 citations
  3. 3Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent, initiation factor 2 alpha-specific protein kinase1993 · 187 citations
  4. 4Regulation of the Double-stranded RNA-Dependent Protein Kinase PKR by RNAs Encoded by a Repeated Sequence in the Epstein-Barr Virus Genome1996 · 42 citations
  5. 5Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase.1990 · 131 citations