Answers are grounded in this paper and cite their sources.
Asymmetric Michael reactions and enantioselective protonations between enones and thiols were catalyzed by a Sc(OTf)(3)-chiral 2,2'-bipyridine complex in water. The remarkable governing of the enantioselectivity for simple introduction of protons despite their abnormally high mobility in water may provide us with new synthetic opportunities as well as significant chemical advances.
No takes yet. Share an insight, caveat, or question.
Kitanosono et al. (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: