Oral Contraceptives and the Risk of Venous Thrombosis
Why the study?
Do oral contraceptives increase the risk of venous thrombosis and cardiovascular events in women?
Population
Women using oral contraceptives
Design
Review
Authors
Discussion
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Member takes
Implication
Supports thrombotic caution with oral contraceptives; leaves open cardiovascular safety of current low-estrogen formulations.
Structured PICO
Do oral contraceptives increase the risk of venous thrombosis and cardiovascular events in women?
P
Population
Women using oral contraceptives
I
Intervention
Oral contraceptives (including lower-estrogen formulations)
O
Outcome
Venous thrombosishard clinical
Historical observations and epidemiologic studies have linked oral contraceptive use to increased risks of venous thrombosis and cardiovascular events, prompting the development of lower-estrogen formulations.
Cite This Study
Vandenbroucke et al. (2001) studied this question.