Why the study?
Does Mosaic compared to Perimount stented aortic xenograft valve replacement improve hemodynamic function in patients requiring aortic valve replacement?
Does Mosaic compared to Perimount stented aortic xenograft valve replacement improve hemodynamic function in patients requiring aortic valve replacement?
Both Mosaic and Perimount stented aortic xenografts provide sufficient hemodynamic function, though Perimount valves showed lower gradients in certain sizes and more pronounced left ventricular mass regression.
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Perimount may be preferred over Mosaic for lower gradients and greater LV mass regression in 23-25 mm sizes; extends RCT evidence on stented aortic xenograft hemodynamics.
Walther et al. (2004) studied this question.
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