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June 1, 1978HeartOpen Access

Long-term haemodynamic evaluation of aortic pericardial xenograft.

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Why the study?

Does aortic valve replacement with pericardial xenografts improve long-term haemodynamic parameters in patients requiring aortic valve replacement?

Population

30 patients who underwent aortic valve replacement with pericardial xenografts

Comparison

Aortic valve replacement with pericardial… vs Preoperative haemodynamic status

Design

Cohort

Follow-up

mean 43.4 months (range 27 to 59 months)

Authors

ATAnand P. TandonThe Honourable Society of Lincoln's InnDSDonald R. SmithUniversity of California, Santa CruzWWW WhitakerUniformed Services University of the Health Sciences

Discussion

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Implication

May support long-term hemodynamic benefits of pericardial xenografts in aortic valve replacement; leaves open comparative durability versus other prostheses.

Structured PICO

Does aortic valve replacement with pericardial xenografts improve long-term haemodynamic parameters in patients requiring aortic valve replacement?

P
Population
30 patients who underwent aortic valve replacement with pericardial xenografts
I
Intervention
Aortic valve replacement with pericardial xenografts (sizes 19, 21, 23, 25, and 27 mm annulus diameter)
C
Comparator
Preoperative haemodynamic status (available in 16 patients)
O
Outcome
Haemodynamic parameters including cardiac output, pulmonary wedge pressure, left ventricular end-diastolic pressure, and peak systolic gradient at a mean interval of 43.4 monthssurrogate

Aortic pericardial xenografts provide significant long-term circulatory improvement and very small transvalvular gradients.

Cite This Study

Tandon et al. (1978) studied this question.

synapsesocial.com/papers/6a8bd482f71b672e3df49c67https://doi.org/10.1136/hrt.40.6.602
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Radiology of homograft aortic valves1969 · 31 citations
  2. 2Clinical and Haemodynamic Results of Aortic Valve Replacement with the Björk-Shiley Tilting Disc Valve Prosthesis1971 · 99 citations
  3. 3A New Tilting Disc Valve Prosthesis1969 · 181 citations
  4. 4Narrow Aortic Root Complicating Aortic Valve Replacement1969 · 32 citations
  5. 5Evaluation of the 21 Mm Björk-Shiley Tilting Disc Valve in Patients with Narrow Aortic Roots: A Clinical, Haemodynamic and Angiographic Study1973 · 39 citations