Why the study?
Do pericardial valves compared to porcine bioprostheses improve long-term clinical outcomes in patients requiring biological valve replacement?
Population
Patients receiving biological valve prostheses, age range 21-85 years, mean age 57.1 years.
Comparison
Pericardial valves vs Porcine bioprostheses
Design
Cohort
Follow-up
mean 62.3 +/- 18.6 months (up to 12 years)
Authors
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Pericardial valves were associated with higher tissue failure; leaves open optimal bioprosthesis choice pending randomized trials.
Do pericardial valves compared to porcine bioprostheses improve long-term clinical outcomes in patients requiring biological valve replacement?
Pericardial valves showed lower rates of thromboembolism and endocarditis but significantly higher rates of primary tissue failure compared to porcine bioprostheses over a 12-year follow-up.
Reichenspurner et al. (1995) studied this question.
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