The medical management of ulcerative colitis is a diifficult and diffuse topic, and the assessment of any therapeutic agent is a most complex task in a disease which varies greatly in severity and extent, not only from patient to patient but also in the same individual from attack to attack. Carefully plainned controlled trials in colitic attacks of comparable severity are necessary for the evaluation of any remedy. No specific treatment has yet been found. The physician possesses a variety of drugs capable of inducing remission in perhaps half the cases treated and has no reliable means of predicting the therapeutic outcome in a particular instance.
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G Watkinson (1961) studied this question.
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