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August 1, 1988Annals of SurgeryOpen Access

Risk Factors for Postoperative Pneumonia

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Why the study?

Does preoperative protein depletion increase the risk of postoperative pneumonia in patients awaiting major elective gastrointestinal surgery?

Population

80 patients awaiting major elective gastrointestinal surgery

Comparison

Protein depletion vs Nonprotein-depleted patients

Design

Cohort

Follow-up

Postoperative hospital stay

Authors

JWJohn A. WindsorUniversity of AucklandGHGraham L. HillAnimal and Plant Health Agency

Discussion

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Implication

Protein depletion was associated with higher pneumonia rates and longer stays after GI surgery; leaves open whether preoperative repletion improves outcomes.

Structured PICO

Does preoperative protein depletion increase the risk of postoperative pneumonia in patients awaiting major elective gastrointestinal surgery?

P
Population
80 patients (42 men, 38 women, median age 64 years, range 15-91 years) awaiting major elective gastrointestinal (G.I.) surgery
I
Intervention
Protein depletion (mean protein loss 36% +/- 3.5 SEM)
C
Comparator
Nonprotein-depleted patients (mean protein loss 2% +/- 1.7 SEM)
O
Outcome
Development of postoperative pneumoniahard clinical

Preoperative protein depletion is associated with impaired respiratory function and is a significant risk factor for postoperative pneumonia and prolonged hospital stay in patients undergoing major gastrointestinal surgery.

Cite This Study

Windsor et al. (1988) studied this question.

synapsesocial.com/papers/6a7f374bdac4de2d60b3add9https://doi.org/10.1097/00000658-198808000-00013
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulmonary Evaluation of Surgical Patients1962 · 212 citations
  2. 2Clinical Significance of Preoperative Nutritional Status in 215 Noncancer Patients1984 · 228 citations
  3. 3Anesthesia in the Morbidly Obese Patient1974 · 21 citations
  4. 4Hydration of fat-free body in protein-depleted patients1985 · 43 citations
  5. 5Maximal respiratory pressures: normal values and relationship to age and sex.1969 · 1,885 citations