Key result
Tricuspid TEER reduces torrential regurgitation to grade 1 with sustained functional gains at 1 year.
Why the study?
Many patients with severe tricuspid regurgitation are ineligible for traditional open-heart surgery due to advanced age, comorbidities, or prior cardiac surgery, making transcatheter tricuspid valve intervention an important minimally invasive alternative.
Does transcatheter edge-to-edge repair reduce tricuspid regurgitation in a patient with a quadricuspid tricuspid valve?
Case Report (n=1)
No
Does transcatheter edge-to-edge repair reduce tricuspid regurgitation in a patient with a quadricuspid tricuspid valve?
Transcatheter edge-to-edge repair is technically feasible and clinically effective for treating severe tricuspid regurgitation in a patient with a rare quadricuspid tricuspid valve.
Supports technical feasibility in quadricuspid anatomy; leaves open durability, safety, and generalizability pending prospective data.
BACKGROUND: Moderate-to-severe tricuspid regurgitation (TR) represents the most prevalent right heart disorder. If left untreated, it may progress to heart failure and elevate mortality risk. Although traditional open-heart surgery remains the gold standard for severe TR, a significant number of patients are considered ineligible due to advanced age, comorbidities, or a history of cardiac surgery. Transcatheter tricuspid valve intervention (TTVI) has emerged as a minimally invasive alternative, with initial studies indicating both safety and efficacy in high-risk populations. We report the case of an 82-year-old patient with a quadricuspid tricuspid valve and torrential TR (grade 5) who was deemed unsuitable for conventional cardiopulmonary bypass surgery. Via a minimally invasive transcatheter approach, two edge-to-edge clips were successfully implanted, achieving effective valve repair. The patient exhibited an favorable postoperative recovery. CONCLUSIONS: The incidence of TR among elderly patients is increasing. For those who do not respond to conservative management and face high surgical risk, transcatheter intervention offers a promising therapeutic alternative to enhance clinical outcomes.
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Yu et al. (2025) conducted a case report in Quadricuspid tricuspid valve with severe tricuspid regurgitation (n=1). Transcatheter tricuspid valve intervention (TTVI) was evaluated on Tricuspid regurgitation severity and heart failure symptoms. Transcatheter edge-to-edge repair successfully reduced torrential tricuspid regurgitation from grade 5 to grade 1 and improved heart failure symptoms from grade III to grade I at one year.
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