Why the study?
Does long-term treatment with trandolapril oppose cardiac remodeling and prolong survival after myocardial infarction in rats?
Does long-term treatment with trandolapril oppose cardiac remodeling and prolong survival after myocardial infarction in rats?
Long-term treatment with trandolapril opposes cardiac remodeling and prolongs survival after myocardial infarction in rats.
Hypothesis-generating in rat MI model; leaves open translation to human remodeling or survival outcomes.
Journal of Cardiovascular Pharmacology™ is a peer reviewed, multidisciplinary journal that publishes original articles and pertinent review articles on basic and clinical aspects of cardiovascular pharmacology. Appropriate subjects include new drug development and evaluation, physiological and pharmacological bases of drug action, metabolism, drug interactions and side effects, clinical results with new and established agents and novel methods. The focus is on pharmacology in its broadest applications, incorporating not only traditional approaches, but new approaches to the development of pharmacological agents and the prevention and treatment of cardiovascular diseases.
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Richer et al. (1992) studied this question.
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