Psoriasis, Gamma-Interferon, and the Acquired Immunodeficiency Syndrome

Letters and Corrections1 January 1987Psoriasis, Gamma-Interferon, and the Acquired Immunodeficiency SyndromeDIETMAR FUCHS, Ph.D., ARNO HAUSEN, Ph.D., GILBERT REIBNEGGER, D.Sc., ERNST R. WERNER, D.Sc., MANFRED P. DIERICH, M.D., HELMUT WACHTER, Ph.D.DIETMAR FUCHS, Ph.D.Search for more papers by this author, ARNO HAUSEN, Ph.D.Search for more papers by this author, GILBERT REIBNEGGER, D.Sc.Search for more papers by this author, ERNST R. WERNER, D.Sc.Search for more papers by this author, MANFRED P. DIERICH, M.D.Search for more papers by this author, HELMUT WACHTER, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-1-165_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The association between the acquired immunodeficiency syndrome (AIDS) and seborrheic dermatitis has been described several times. It has also indicated that enhanced interferon levels might serve as an important factor associated with flares of psoriasis. On the one hand, patients treated with alpha-interferon have exacerbation of severe psoriasis (1), and on the other hand, gamma-interferon and enhanced expression of class-II major histocompatibility complex antigens on Langerhans' cells in the epidermis are expected to trigger or exacerbate psoriasis (2). The latter observations are in agreement with data showing successful treatment of severe recalcitrant psoriasis by immunosuppressive protocols (methotrexate...References1. BAKERGRIFFITHSFRYVALDIMARSSON BCLH. Psoriasis and interferon. Lancet. 1986;2:342. CrossrefMedlineGoogle Scholar2. QUESADAGUTTERMAN JJ. Psoriasis and alpha-interferon. Lancet. 1986;1:1466-8. CrossrefMedlineGoogle Scholar3. FUCHSHAUSENREIBNEGGER DAG. Urinary neopterin in the diagnosis of acquired immunodeficiency syndrome. Eur J Clin Microbiol. 1984;3:70-1. CrossrefMedlineGoogle Scholar4. PAIETTASALTZMANKLEINFRIEDLANDWIERNIKSTEIN EBRGPH. Expression of activation antigen on lymphocytes in the acquired immunodeficiency syndrome [Letter]. Ann Intern Med. 1986;104:890-1. LinkGoogle Scholar5. GASCONZOUMBASYOUNG PNN. Immunologic abnormalities in patients receiving multiple blood transfusions. Ann Intern Med. 1984;100:173-7. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Innsbruck Ludwig Boltzmann Institute for AIDS Research A-6020 Innsbruck Austria PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPsoriasis in HIV infection: an updateHIV Infection Increases the Risk of Incident Psoriasis: A Nationwide Population-Based Cohort Study in TaiwanHIV-associated psoriasis: pathogenesis, clinical features, and managementProvozierte Dermatosen bei HIV-InfektionPsoriasis and Psoriatic Arthritis Associated with Human Immunodeficiency Virus InfectionPsoriatic arthritis and acquired immunodeficiency syndromeRheumatic manifestations of human immunodeficiency virus infection 1 January 1987Volume 106, Issue 1Page: 165-165KeywordsAIDSAntigensImmunosuppressivesInterferonsLangerhans cellsMajor histocompatibility complexMethotrexatePsoriasis Issue Published: 1 January 1987 PDF DownloadLoading ...