Cardiac tumors are predominantly benign primary tumors, most commonly myxomas in the left atrium, which have a good prognosis with early surgical intervention despite the potential for fatal hemodynamic disturbances.
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Early surgical referral for left atrial myxomas remains standard; leaves open need for multicenter registries on rare malignant cases.
To analyze the relation between the pathological changes and the clinical manifestations and the prognosis of cardiac tumors through the pathological study on 42 cases with cardiac tumor, in order to improve the knowledge of the tumors, to make early diagnosis and to raise the curative ratio. 42 confirmed cardiac tumors of our department were selected, among which 41 was surgical specimen and 1 was autopsy. The study was performed by using the common and special histochemical staining. 41 is primary and 1 is secondary which is a metastazed hepatocelular carcinoma. In the primary ones, 39 (95.1%) is benign, including myxoma, fibroma, rhabdomyoma and pericardial cyst, while 2 (4.9%) is malignant, including neurolemmafibrosarcoma and malignant mesothelioma. In the myxomas, female patients occupy 75%, 91.7% exists in the left atrium and every one has got a peduncle adhesive to the fossa ovalis or adjacency of the atrial septum. The results of the pathological and prognostic study showes cardiac tumors are quite different from the tumors in other sites, i.e., even benign ones could cause fatal hemodynamic disturbance. Hence early diagnosis and early operation are necessary and if in such instance, the prognosis of most of the benign ones would be good. But the prognosis of the malignant tumors is worst. The myxomas are different from the organized thrombi in heart cavity. And also the criteria of diagnosis and differential diagnosis are discussed.
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Liang et al. (1996) studied this question.
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