Why the study?
Do cord blood IGF-I and IGFBP-1 levels correlate with echocardiographic findings of hypertrophic cardiomyopathy in infants of diabetic mothers?
Population
69 neonates born to diabetic mothers admitted to the neonatal intensive care unit at Ain Shams University…
Design
Cross-sectional
Authors
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Hypothesis-generating for IGF axis in neonatal hypertrophic cardiomyopathy; prospective studies needed before clinical adoption.
Do cord blood IGF-I and IGFBP-1 levels correlate with echocardiographic findings of hypertrophic cardiomyopathy in infants of diabetic mothers?
In infants of diabetic mothers, birth weight and cord blood IGF-I/IGFBP-1 levels correlate with the presence of hypertrophic cardiomyopathy, which is highly prevalent in those with suboptimal maternal glycemic control.
El-Ganzoury et al. (2011) studied this question.
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