Why the study?
Does maternal gestational diabetes alter early diastolic intraventricular pressure differences and myocardial strain in infants?
Does maternal gestational diabetes alter early diastolic intraventricular pressure differences and myocardial strain in infants?
Infants born to mothers with gestational diabetes exhibit increased ventricular sucking force (IVPD, IVPG) and endocardial global circumferential strain, suggesting early cardiac metabolic adaptations to a hyperglycemic environment.
May signal early cardiac adaptations in IGDM; hypothesis-generating and requires prospective validation before any clinical implications.
Ventricular sucking force, measured as the IVPD, IVPG, and endocardial GCS, were higher in IGDM than in the controls. A hyperglycemic environment during pregnancy leads to impaired cardiac performance in IGDM, compared with control infants. IGDM might have favorable systolic and diastolic cardiac performance due to cardiac metabolic adaptations occurring before poor glucose control causes impaired cardiac performance.
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Iwashima et al. (2019) studied this question.
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