Why the study?
The impact of chronic kidney disease on long-term outcomes after AMI in the era of modern primary PCI and optimal medical therapy remains debated.
Does the presence of chronic kidney disease increase in-hospital and 3-year mortality and MACE in patients with acute myocardial infarction treated by contemporary PCI and optimal medical therapy?
Population
3,281 AMI patients treated with contemporary PCI and optimal medical therapy
Comparison
No CKD vs moderate CKD vs severe CKD
Design
Observational cohort study (J-MINUET Study)
Follow-up
3 years
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CKD still flags high residual post-AMI mortality despite modern PCI; confirms independent prognostic value and leaves open targeted risk-reduction trials.
Does the presence of chronic kidney disease increase in-hospital and 3-year mortality and MACE in patients with acute myocardial infarction treated by contemporary PCI and optimal medical therapy?
In the contemporary era of primary PCI and optimal medical therapy, chronic kidney disease remains a strong, independent predictor of in-hospital and 3-year mortality and MACE following acute myocardial infarction.
A 2021 study studied this question.
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