What question did this study set out to answer?

To evaluate the feasibility and efficacy of an anatomically guided atrial ganglionated plexus ablation strategy monitored by extracardiac vagal stimulation for treating vagally mediated atrioventricular block.

February 10, 2021HeartRhythm Case ReportsOpen Access

Anatomically guided atrial ganglionated plexus ablation evaluated by extracardiac vagal stimulation for vagally mediated atrioventricular block

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Why the study?

There is no consensus on the best strategy for identifying atrial ganglionated plexus sites or the extension of ablation necessary to attenuate vagal activity in functional bradycardia or neurally mediated syncope.

Authors

ÁSÁlvaro Valentim Lima SarabandaInstituto de Cardiologia do Distrito Federal SMSissy Lara de MeloUniversidade de São Paulo EREsteban Wisnivesky Rocca RivarolaUniversidade de São Paulo

Discussion

Member takes

Implication

Should not yet change practice for functional AV block; leaves open anatomically guided GP ablation as a potential pacing alternative.

Key Points

To evaluate the feasibility and efficacy of an anatomically guided atrial ganglionated plexus ablation strategy monitored by extracardiac vagal stimulation for treating vagally mediated atrioventricular block.
Catheter ablation targeting atrial ganglionated plexuses using an anatomically guided approach in patients with functional bradycardia or neurally mediated syncope.
Application of extracardiac vagal stimulation to assess acute attenuation of parasympathetic vagal responses.
Demonstrates that anatomically guided catheter ablation successfully attenuates hyperactive vagal tone in patients with vagally mediated atrioventricular block.
Confirms that extracardiac vagal stimulation serves as a functional real-time tool to verify the adequacy and extent of autonomic denervation.

Cite This Study

Sarabanda et al. (2021) studied this question.

synapsesocial.com/papers/6a7f67f811d2ce75ff8b1fb1 https://doi.org/10.1016/j.hrcr.2021.02.002

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Anatomically guided atrial ganglionated plexus ablation evaluated by extracardiac vagal stimulation for vagally mediated atrioventricular block

Discussion

Member takes

Implication

Key Points

Cite This Study

Anatomically guided atrial ganglionated plexus ablation evaluated by extracardiac vagal stimulation for vagally mediated atrioventricular block

Discussion

Member takes

Implication

Key Points

Cite This Study

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