Differential effect of ganglionic plexi ablation in a patient with neurally mediated syncope and intermittent atrioventricular block
Population
35-year-old female with frequent symptomatic episodes of advanced AV block and severe neurally mediated…
Design
Case_report
Follow-up
10 months
Authors
Discussion
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Member takes
Implication
May support selective inferior left GP ablation to avoid pacing in neurally mediated syncope; hypothesis-generating and requires prospective trials.
Structured PICO
P
Population
35-year-old female with frequent symptomatic episodes of advanced AV block and severe neurally mediated syncope (NMS)
I
Intervention
Anatomically guided radiofrequency catheter ablation (RFA) at empirical sites of ganglionic plexi (GPs)
O
Outcome
Heart rate, PR interval, and bradycardia episodes during follow-up
This case demonstrates the differential effects of ganglionic plexi ablation on SA and AV nodal function, highlighting the potential of targeting the postero-inferior left atrium to treat cardio-inhibitory neurally mediated syncope without requiring pacemaker implantation.
Cite This Study
Fukunaga et al. (2016) studied this question.