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Does shorter deceleration time of the mitral inflow predict cardiovascular death in patients with restrictive left ventricular filling and depressed systolic function?
Does shorter deceleration time of the mitral inflow predict cardiovascular death in patients with restrictive left ventricular filling and depressed systolic function?
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A deceleration time of the early wave of the mitral inflow <140 ms is a practical echocardiographic parameter that identifies patients with left ventricular systolic dysfunction and restrictive filling at the highest risk of cardiac death.
The survival, clinical and echocardiographic variables and the predictors of cardiovascular death were determined for a group of 168 patients (mean age 63+/-13 years; 65 females; mean left ventricular ejection fraction 32+/-10%) with restrictive filling of the left ventricle and depressed systolic function after a mean follow-up period of 2.7+/-1 years. Shorter deceleration time (DT) of the mitral inflow was the only variable significantly different between survivors and nonsurvivors (p<0.05) and the only predictor of death found by multivariate logistic regression analysis (odds ratio 2.2, 95% confidence interval 1.7-3.6). In this patient population, a DT of the early wave of the mitral inflow <140 ms identified the patients with the highest risk of cardiac death. DT is a practical echocardiographic parameter for risk stratification of patients with significant left ventricular systolic dysfunction and restrictive filling of the left ventricle.
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Boccalandro et al. (2004) studied this question.
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