Key result
The restrictive mitral filling pattern was associated with higher all-cause mortality than the non-restrictive filling pattern in patients with heart failure (HR 2.42; 95% CI 2.06-2.83).
Why the study?
Does the restrictive mitral filling pattern predict mortality independently of LVEF in patients with heart failure?
Meta-Analysis (n=3,540)
Yes
Does the restrictive mitral filling pattern predict mortality independently of LVEF in patients with heart failure?
Hazard Ratio: 2.42 (95% CI 2.06–2.83)
The restrictive mitral filling pattern on echocardiography is a powerful predictor of mortality in heart failure patients, independent of LVEF and age.
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Reinforces restrictive filling as a prognostic marker in HF; confirms independence from LVEF.
Doughty et al. (2008) conducted a meta-analysis in Heart failure (n=3,540). Restrictive mitral filling pattern vs. Non-restrictive filling pattern was evaluated on All-cause mortality (HR 2.42, 95% CI 2.06-2.83). The restrictive mitral filling pattern was associated with higher all-cause mortality than the non-restrictive filling pattern in patients with heart failure (HR 2.42; 95% CI 2.06-2.83).
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