Why the study?
Does nitric oxide administration improve survival time in a feline model of splanchnic artery occlusion shock?
Population
Anesthetized cats subjected to total occlusion of the celiac, superior mesenteric, and inferior mesenteric…
Comparison
Nitric oxide solution or acidified sodium… vs Vehicle or NaNO2 at pH 7.4
Design
Preclinical
Follow-up
Approximately 60 minutes after reperfusion
Authors
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NO may extend survival in feline SAO shock; leaves open translation to human ischemic conditions.
Does nitric oxide administration improve survival time in a feline model of splanchnic artery occlusion shock?
Nitric oxide administration improves survival and exerts cytoprotective effects in a feline model of splanchnic ischemic shock.
Aoki et al. (1990) studied this question.
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