What question did this study set out to answer?

To describe the global epidemiology, clinical features, and diagnostic challenges associated with brain-eating amoeba infections over a recent ten-year period.

February 9, 2023International Journal of Environmental Research and Public HealthOpen Access

Systematic Review of Brain-Eating Amoeba: A Decade Update

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Authors

MZMohd ‘Ammar Ihsan Ahmad ZamzuriMinistry of Health FMFarah Nabila Abd MajidNational University of Malaysia MMMassitah MihatMinistry of Health

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Implication

Systematic review reveals a 72.7% mortality rate in brain-eating amoeba cases, highlighting the need for rapid diagnostic testing following freshwater exposure.

Key Points

To describe the global epidemiology, clinical features, and diagnostic challenges associated with brain-eating amoeba infections over a recent ten-year period.
Searched PubMed, Web of Science, Scopus, and OVID databases for studies published between 2013 and December 31, 2022.
Conducted quality assessments by two independent reviewers, selecting 21 eligible studies for qualitative analysis out of 461 screened records.
Documented cases across a worldwide distribution spanning patients aged 11 days to 75 years, with an overall mortality rate of 72.7%.
Identified recreational freshwater activities and nasal irrigation as primary exposure routes preceding acute onset of fever, headache, vomiting, and subsequent neurological sequelae.
Reported that clinical presentations frequently mimic bacterial meningitis, requiring confirmation via direct amoeba visualization or polymerase chain reaction.

Cite This Study

Zamzuri et al. (2023) studied this question.

synapsesocial.com/papers/6a7f81ca53b9c9cf1aa556df https://doi.org/10.3390/ijerph20043021

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Implication

Systematic review reveals a 72.7% mortality rate in brain-eating amoeba cases, highlighting the need for rapid diagnostic testing following freshwater exposure.

Systematic Review of Brain-Eating Amoeba: A Decade Update

Discussion

Member takes

Implication

Key Points

Cite This Study

Systematic Review of Brain-Eating Amoeba: A Decade Update

Discussion

Member takes

Implication

Key Points

Cite This Study

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