October 11, 2011Heart
Long-term prognostic value of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction
Why the study?
Does myocardial salvage index assessed by CMR predict long-term clinical outcomes in patients with STEMI undergoing primary angioplasty?
Population
208 consecutive patients with ST-elevation myocardial infarction undergoing primary angioplasty <12 h after…
Comparison
Myocardial salvage index ≥ median assessed by… vs Myocardial salvage index (MSI) < median
Design
Cohort
Follow-up
median 18.5 months (IQR 13.8 to 20.8)
Authors
Discussion
Loading...
Member takes
Overview
MSI by CMR associated with lower long-term MACE in STEMI; leaves open its validation as a surrogate endpoint.
Structured PICO
Does myocardial salvage index assessed by CMR predict long-term clinical outcomes in patients with STEMI undergoing primary angioplasty?
P
Population
208 consecutive patients with ST-elevation myocardial infarction (STEMI) undergoing primary angioplasty <12 h after symptom onset
I
Intervention
Myocardial salvage index (MSI) ≥ median assessed by T2-weighted and contrast-enhanced cardiovascular magnetic resonance (CMR)
C
Comparator
Myocardial salvage index (MSI) < median
O
Outcome
Major adverse cardiovascular events defined as death, reinfarction and new congestive heart failure at long-term follow-upcomposite
Myocardial salvage index assessed by CMR is a strong independent predictor of long-term clinical outcomes in patients with reperfused STEMI, supporting its use as a surrogate endpoint in clinical trials.
Cite This Study
Eitel et al. (2011) studied this question.