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February 19, 2008Journal of Surgical Oncology

Diagnosis and management of synovial sarcoma

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Why the study?

What are the current diagnostic and management strategies for synovial sarcoma?

Population

Patients with synovial sarcoma

Design

Review

Authors

FEFritz C. EilberSDSarah Dry

Discussion

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Overview

Supports multidisciplinary care in synovial sarcoma; leaves open development of targeted systemic therapies against distant metastasis.

Structured PICO

What are the current diagnostic and management strategies for synovial sarcoma?

P
Population
Patients with synovial sarcoma (soft tissue sarcoma, most commonly in extremities of young adults, high grade with characteristic translocation X;18;p11;q11)
I
Intervention
Surgery, radiation therapy, and ifosfamide-based chemotherapy
O
Outcome
Local control, distant metastasis, and survival

While surgery and radiation provide local control for synovial sarcoma, distant metastasis remains a challenge, highlighting the need for less toxic and more targeted systemic therapies beyond ifosfamide.

Cite This Study

Eilber et al. (2008) studied this question.

synapsesocial.com/papers/6a7f923b24cfba499c4069f7https://doi.org/10.1002/jso.20974
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