Key result
Seasonal variation links to fluctuations in total serum cholesterol among healthy young adults.
Observational
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Article1 March 1961OBSERVATIONS ON SEASONAL VARIATIONS IN TOTAL SERUM CHOLESTEROL LEVEL AMONG HEALTHY YOUNG PRISONERSCAROLINE BEDELL THOMAS, M.D., F.A.C.P., HENRY W. D. HOLLJES, M.D., F.C.C.P., FRIEDA F. EISENBERG, A.B.CAROLINE BEDELL THOMAS, M.D., F.A.C.P., HENRY W. D. HOLLJES, M.D., F.C.C.P., FRIEDA F. EISENBERG, A.B.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-413 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe total serum cholesterol level in a given individual at any particular point in time is the result of numerous technical and biologic variables.1-5§Many different methods of chemical analysis of the total cholesterol content of blood serum have been described and compared, both in terms of absolute values and of reproducibility; the technical aspects of cholesterol variability, however, do not concern us here. The biologic factors which influence the level of cholesterol are of even greater diversity and importance. The effects of age, sex, heredity, and diet have been well documented. In contrast, scant attention has been paid to...Bibliography1. . Evaluation of serum lipoprotein and cholesterol measurements as predictors of clinical complications of atherosclerosis: report of a coöperative study of lipoproteins and atherosclerosis. Circulation 14: 691, 1956. CrossrefMedlineGoogle Scholar2. ThomasEisenberg CBFF: Observations on the variability of total serum cholesterol in Johns Hopkins medical students. J. Chron. Dis. 6: 1, 1957. CrossrefMedlineGoogle Scholar3. LewisOlmstedPageLawryMannStareHanigLaufferGordonMoore LAFIHEYGVFJMMATFE: Serum lipid levels in normal persons: findings of a coöperative study of lipoproteins and atherosclerosis. Circulation 16: 227, 1957. CrossrefMedlineGoogle Scholar4. ThomasEisenberg CBFF: Variability of cholesterol levels in individual Johns Hopkins medical students with observations on stopping smoking, vitamin B12 administration, and acute infection. Bull. Johns Hopkins Hosp. 105: 14, 1959. MedlineGoogle Scholar5. Gordon H: The regulation of the human serum-cholesterol level. Postgrad. Med. J. 35: 186, 1959. CrossrefMedlineGoogle Scholar6. Thomas CB: Characteristics of the individual as guideposts to the prevention of heart disease. Ann. Intern. Med. 47: 389, 1957. LinkGoogle Scholar7. Thomas CB: Observations on some possible precursors of essential hypertension and coronary artery disease. V. Hypercholesteremia in healthy young adults. Amer. J. Med. Sci. 232: 389, 1956. CrossrefMedlineGoogle Scholar8. ThomasMurphy CBEA: Further studies on cholesterol levels in the Johns Hopkins medical students: the effect of stress at examination. J. Chron. Dis. 8: 661, 1958. CrossrefMedlineGoogle Scholar9. WeissDlinRollinFisherBepler EBHKCR: Emotional factors in coronary occlusion. Arch. Intern. Med. 99: 628, 1957. CrossrefGoogle Scholar10. Weiss E: The anniversary reaction in heart disease. Heart Bull. 7: 70, 1958. MedlineGoogle Scholar11. MannTeelHayesMcNallyBruno GVKOAD: Exercise in the disposition of dietary calories; regulation of serum lipoprotein and cholesterol levels in human subjects. New Engl. J. Med. 253: 349, 1955. CrossrefMedlineGoogle Scholar12. TaylorAndersonKeys HLJIA: Physical activity, serum cholesterol, and other lipids in man. Proc. Soc. Exp. Biol. Med. 95: 383, 1957. CrossrefMedlineGoogle Scholar13. ThomasGam CBSM: Degree of obesity and serum cholesterol level. Science 131: 42, 1960. CrossrefMedlineGoogle Scholar14. HatchAbellKendall FTLLFE: Effects of restriction of dietary fat and lipoproteins in patients with hypertension. Amer. J. Med. 19: 48, 1955. CrossrefMedlineGoogle Scholar15. Currie AN: The cholesterol of blood in malignant disease. Brit. J. Exp. Path. 5: 293, 1924. Google Scholar16. McEachernGilmour JMCR: Studies in cholesterol metabolism. 2. Blood cholesterol in various conditions. Canad. Med. Ass. J. 26: 158, 1932. MedlineGoogle Scholar17. MeansAndrews TMFN: The influence of season on blood plasma cholesterol in the ewe. Amer. J. Vet. Res. 19: 295, 1958. MedlineGoogle Scholar18. MacKinnonMacKinnon ILPC: Seasonal rhythm in the morphology of the suprarenal cortex in women of childbearing age. J. Endocrin. 17: 456, 1958. CrossrefMedlineGoogle Scholar19. Osiba S: The seasonal variation of basal metabolism and activity of thyroid gland in man. Jap. J. Physiol. 7: 355, 1957. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication August 17, 1960.From the Johns Hopkins University School of Medicine, Baltimore, Maryland.†Supported by Research Grant H-1891 from the National Heart Institute.‡Associate in Medicine, The University of Maryland School of Medicine.§In view of the extensive literature, only selected references which themselves have pertinent bibliographies are given here.Requests for reprints should be addressed to Caroline B. Thomas, M.D., 700 North Wolfe St., Baltimore 5, Maryland. 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GLEASON, Ph.D.Interferences in Diagnostic Biochemical ProceduresProblems in the interpretation of serum cholesterol valuesChronobiology of the Life SequenceInterpretation of HyperlipidemiasFactors affecting the mean serum cholesterolCHOLESTEROL METABOLISM IN THE BABOON*,†Seasonal variation of non-embolic cerebral infarctionClinical MedicineREFERENCESSeasonal variation in serum lipids, and incidence and mortality of ischaemic heart diseaseEffects of an exercise program on plasma lipids of senior air force officersAtherosclerosis and CholesterolFOLATE METABOLISM AND IRON DEFICIENCYSERUM-CHOLESTEROL IN THE ARCTICSeasonal variation in serum cholesterol concentrationSeasonal variation in the cholesterol content of the adrenals in ratsSerum lipid changes following myocardial infarctionHYPOCHOLESTEROLÆMIC EFFECT OF AN ANABOLIC STEROID, METHALONEThyroxine analogues as hypocholesterolemic agentsTHE EFFECT OF METEOROLOGICAL PHENOMENA ON ACUTE MYOCARDIAL INFARCTION IN STAMFORD, CONNECTICUTUse of an anion exchange resin in treatment of two siblings with familial hypercholesterolemiaExercise and Prevention of Heart DiseaseA Longitudinal Study of Coronary Heart DiseaseSeasonal Variations in Thermal Fragility of Erythrocytes in Man : Influence of Age and SexRELATION OF SERUM CHOLESTEROL TO FOOD AND VITAMIN HABITSNormal variations in blood constituentsObservations on Serum Cholesterol Levels in the Twin Population of Evans County, GeorgiaOne Year of Sodium Dextrothyroxine Therapy for HypercholesterolemiaThyroid Analogs as Cholesteropenic AgentsSerum β-Lipoprotein Lipids and Protein in Normal Subjects of Different Sex and Age 1 March 1961Volume 54, Issue 3Page: 413-430KeywordsBiologicsBloodChemical analysisCholesterolDietEmotionsHeartHeredityReproducibilityResearch grants Issue Published: 1 March 1961 PDF DownloadLoading ...
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Caroline Bedell Thomas (1961) conducted an observational in Healthy young prisoners. Seasonal variation was evaluated on Total serum cholesterol level.
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