Why the study?
Does benidipine-based antihypertensive treatment reduce cardiovascular events and achieve blood pressure targets in elderly hypertensive patients?
Population
8,897 hypertensive patients aged ≥65 years in Japan (5,092 aged 65-74 years, 3,805 aged ≥75 years)
Design
Cohort
Follow-up
3 years
Authors
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May support targeting on-treatment SBP <160 mmHg in elderly hypertensives; extends observational data but leaves causal benefit of intensification open.
Does benidipine-based antihypertensive treatment reduce cardiovascular events and achieve blood pressure targets in elderly hypertensive patients?
In elderly Japanese hypertensive patients, benidipine-based treatment effectively lowered blood pressure, and failure to achieve on-treatment SBP <160 mmHg was associated with higher cardiovascular risk.
Saito et al. (2011) studied this question.