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November 1, 1996Diabetic Medicine

Increased Mortality Associated with Diabetic Foot Ulcer

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Why the study?

Does the development of a foot ulcer increase short-term mortality in diabetic veterans?

Population

725 veterans of the American military services with diabetes mellitus participating in a prospective study…

Comparison

Development of foot ulcer (n=88) vs No foot ulcer

Design

Cohort

Follow-up

Mean 691.8 days (+/-SD 339.9, range 28-1436 days)

Authors

Edward J. BoykoEdward J. BoykoBoston UniversityJAJessie H. AhroniVA Puget Sound Health Care SystemDSDouglas G. SmithHenry M. Jackson Foundation

Discussion

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Implication

May prompt closer foot surveillance in diabetic veterans; hypothesis-generating for whether prevention improves survival.

Structured PICO

Does the development of a foot ulcer increase short-term mortality in diabetic veterans?

P
Population
725 veterans of the American military services with diabetes mellitus participating in a prospective study of risk factors for lower extremity complications
I
Intervention
Development of foot ulcer (n=88)
C
Comparator
No foot ulcer
O
Outcome
Short-term mortality (death)hard clinical

Diabetic foot ulcers are associated with a greater than two-fold increased risk of short-term mortality, independent of other risk factors.

Cite This Study

Boyko et al. (1996) studied this question.

synapsesocial.com/papers/6a7fb12d044998269cd7715ahttps://doi.org/10.1002/(sici)1096-9136(199611)13:11<967::aid-dia266>3.0.co;2-k
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diabetic Foot Ulcers Are Clinical Marker of Disease Burden in People With Diabetes and Heart Failure2026
  2. 2Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study2026
  3. 3Mortality Related to Diabetic Foot Ulcer: A Comprehensive Review2025
  4. 4Evaluation of Clinical and Lifestyle Risk Factors Contributing to the Disease Burden of Diabetic Foot Ulcers: A Prospective Observational Study2025
  5. 5Incidence and predictors of diabetic foot ulcer among patients with diabetes mellitus in a diabetic follow-up clinic in Central Ethiopia: a retrospective follow-up study2024 · 3 citations