Population
Preterm (99 ± 1 days gestation), near-term fetal sheep (119 ± 0 days gestation), and adult sheep
Comparison
Telemetry-based nerve amplifier recording of… vs Comparison across age groups
Design
Preclinical
Authors
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Indicates maturing central sympathetic control; leaves open translation to human fetal cardiovascular regulation.
The delay between diastole and the peak in renal sympathetic nerve activity decreases from fetal life to adulthood, indicating continuing maturation of central neural circuitry.
Booth et al. (2010) studied this question.
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