Population
Seven unanesthetized fetal sheep (aged 127-136 days)
Comparison
Observation of fetal behavioral states vs Comparisons across different behavioral states
Design
Preclinical
Follow-up
1-3 days after surgery
Authors
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Animal data on fetal state effects require validation before clinical consideration; leaves open translation of state-dependent cardiovascular control to human neonates.
Fetal behavioral states significantly affect renal sympathetic nerve activity, mean arterial pressure, and heart rate in fetal sheep, indicating state-dependent cardiovascular control.
Lumbers et al. (2003) studied this question.
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