Why the study?
The influence of digitalis use on mortality in patients with non-valvular atrial fibrillation remains controversial.
Does digitalis use increase all-cause death in patients with non-valvular atrial fibrillation?
Population
7,018 outpatients with NVAF from 158 institutions
Comparison
Digitalis use vs no digitalis use
Design
Registry subanalysis with propensity score-matching
Follow-up
2 years
Authors
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Should not yet change digitalis prescribing in NVAF; leaves open residual confounding behind prior mortality signals.
Does digitalis use increase all-cause death in patients with non-valvular atrial fibrillation?
Digitalis use is not independently associated with increased all-cause mortality in patients with non-valvular atrial fibrillation after adjusting for clinical confounders.
Kodani et al. (2019) studied this question.
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