Why the study?
Hand, foot and mouth disease is a transmissible infectious disease caused by human enteroviruses, but the features of severe cases caused by EV-A71 or CV-A16 in Shanghai, China needed description.
In children with severe HFMD caused by EV-A71 or CV-A16, IVIG treatment appeared beneficial in shortening the duration of illness episodes.
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May shorten illness in severe pediatric HFMD; hypothesis-generating and requires randomized confirmation before practice change.
Cai et al. (2019) studied this question.
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