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July 1, 1999Clinical Infectious Diseases

Clinical Spectrum of Enterovirus 71 Infection in Children in Southern Taiwan, with an Emphasis on Neurological Complications

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Population

97 children with virus culture-proven enterovirus 71 infections during a 1998 outbreak in Southern Taiwan…

Design

Case_series

Authors

SWShih‐Min WangChang Gung University of Science and TechnologyCLChing‐Chuan LiuNational Cheng Kung University HospitalHTHui‐Wan TsengNational Cheng Kung University Hospital

Discussion

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Implication

May prompt CNS vigilance in pediatric EV71; leaves open optimal early interventions.

Structured PICO

P
Population
97 children with virus culture-proven enterovirus 71 (EV71) infections during a 1998 outbreak in Southern Taiwan, 87% younger than 5 years.
O
Outcome
Clinical spectrums and laboratory findings, with an emphasis on neurological complications

Enterovirus 71 infection in children can cause severe brain stem encephalitis that may rapidly progress to neurogenic shock and pulmonary edema, necessitating early aggressive treatment.

Cite This Study

Wang et al. (1999) studied this question.

synapsesocial.com/papers/6a6f6a8887f9210571271fffhttps://doi.org/10.1086/520149
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outbreak of enterovirus 71 infection in Victoria, Australia, with a high incidence of neurologic involvement1988 · 251 citations
  2. 2Enterovirus 71 Infection: Report of an Outbreak with Two Cases of Paralysis and a Review of the Literature1981 · 92 citations
  3. 3Fatal enterovirus type 71 infection1995 · 62 citations
  4. 4Monoplegia caused by Enterovirus 711987 · 123 citations
  5. 5Poliovirus Spreads from Muscle to the Central Nervous System by Neural Pathways1992 · 164 citations