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August 19, 2014Medicine & Science in Sports & Exercise

Effect of Prolonged Sitting and Breaks in Sitting Time on Endothelial Function

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Why the study?

Does breaking sitting time with brief periods of light activity prevent endothelial dysfunction in nonobese men?

Population

12 nonobese men, mean age 24.2 ± 4.2 years

Comparison

Breaking sitting time with 5 minutes of walking… vs Continuous sitting on a firmly cushioned chair…

Design

RCT, randomized

Follow-up

3 hours

Authors

STSaurabh S. ThosarSBSylvanna L. BielkoKMKieren J. Mather

Discussion

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Overview

Light activity breaks may preserve lower-limb endothelial function during prolonged sitting; extends RCT evidence on acute sedentary vascular effects.

Structured PICO

Does breaking sitting time with brief periods of light activity prevent endothelial dysfunction in nonobese men?

P
Population
12 nonobese men, mean age 24.2 ± 4.2 years
I
Intervention
Breaking sitting time with 5 minutes of walking on a treadmill at 2 mph at 30 min, 1 h 30 min, and 2 h 30 min during a 3-hour sitting interval
C
Comparator
Continuous sitting on a firmly cushioned chair for 3 hours without moving lower extremities
O
Outcome
Superficial femoral artery (SFA) flow-mediated dilation (FMD) and shear rates at baseline, 1 h, 2 h, and 3 hsurrogate

Breaking prolonged sitting with 5 minutes of light walking every hour prevents the decline in lower extremity endothelial function caused by continuous sitting.

Cite This Study

Thosar et al. (2014) studied this question.

synapsesocial.com/papers/6a7fdfcf9ec92753f80feb46https://doi.org/10.1249/mss.0000000000000479
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