August 1, 1982Annals of Internal Medicine
Acute Effects of Alcohol in Patients with Congestive Heart Failure
Why the study?
Does a single moderate dose of alcohol affect hemodynamic and echocardiographic variables in patients with NYHA class III-IV congestive heart failure?
Population
8 patients with New York Heart Association Functional Class III-IV congestive heart failure
Comparison
Single dose of alcohol, 0.9 g/kg body weight… vs Baseline measurements
Design
Case_series
Follow-up
90 minutes
Authors
Discussion
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Member takes
Implication
Should not change practice in severe HF; leaves open whether moderate alcohol safely aids afterload reduction in larger trials.
Structured PICO
Does a single moderate dose of alcohol affect hemodynamic and echocardiographic variables in patients with NYHA class III-IV congestive heart failure?
P
Population
8 patients with New York Heart Association Functional Class III-IV congestive heart failure
I
Intervention
Single dose of alcohol, 0.9 g/kg body weight, administered as 80 proof vodka
C
Comparator
Baseline measurements (before-and-after design, no separate control group)
O
Outcome
Hemodynamic and echocardiographic variables measured at 30-minute intervals over 90 minutessurrogate
A single moderate dose of alcohol safely reduces afterload without acutely deteriorating cardiac performance in patients with severe heart failure.
Cite This Study
Barry Greenberg (1982) studied this question.