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April 15, 2003Journal of Clinical Oncology

Synovial Sarcoma of Childhood and Adolescence: A Multicenter, Multivariate Analysis of Outcome

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Population

219 children and adolescents with synovial sarcoma

Design

Cohort

Follow-up

median 6.6 years (range, 0.5 to 30.7 years)

Authors

MOM. Fatih OkcuBaylor College of MedicineMMMark F. MunsellThe University of Texas MD Anderson Cancer CenterJTJ. TreunerOlgahospital

Discussion

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Implication

Identifies high-risk subgroups with poor survival; hypothesis-generating for risk-stratified trials but should not yet change practice.

Structured PICO

P
Population
219 children and adolescents with synovial sarcoma
O
Outcome
Overall survival and event-free survivalhard clinical

Clinical group, tumor size, and invasiveness are important prognostic factors for overall survival in children and adolescents with synovial sarcoma.

Cite This Study

Okcu et al. (2003) studied this question.

synapsesocial.com/papers/6a7ff19d1c96fcc8ad700662https://doi.org/10.1200/jco.2003.07.008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Synovial sarcoma: Report of a series of 25 consecutive children from a single institution1999 · 55 citations
  2. 2Synovial Sarcoma: A Multivariate Analysis of Prognostic Factors in 112 Patients With Primary Localized Tumors of the Extremity2000 · 321 citations
  3. 3Synovial sarcoma in children and adolescents: the St Jude Children's Research Hospital experience.1994 · 109 citations
  4. 4Prognostic Factors in Localized Primary Synovial Sarcoma: A Multicenter Study of 128 Adult Patients2001 · 291 citations
  5. 5Synovial Sarcoma: A Clinicopathologic, Staging, and Prognostic Assessment2000 · 360 citations