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July 1, 2007Journal of Cardiovascular Medicine

Long-term follow-up and risk assessment of arrhythmogenic right ventricular dysplasia/cardiomyopathy: personal experience from different primary and tertiary centres

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Why the study?

What is the long-term clinical course and what are the risk factors for sudden cardiac death in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy?

Population

313 patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy, mean age 44.8 +/- 16.5 years…

Design

Cohort

Follow-up

8.5 years

Authors

SPStefan PetersUniversität der Bundeswehr München

Discussion

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Implication

Low mortality in ARVD/C supports conservative monitoring; LV dysfunction association with SCD is hypothesis-generating and needs prospective validation.

Structured PICO

What is the long-term clinical course and what are the risk factors for sudden cardiac death in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy?

P
Population
313 patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C), mean age 44.8 +/- 16.5 years, 197 males. Symptoms included aborted SCD (7%), ventricular arrhythmias (47%), chest pain (42%), syncopes (17%), and atrial arrhythmias (12%).
O
Outcome
Sudden cardiac death (SCD) and end-stage heart failurehard clinical

In patients with ARVD/C, the clinical course is characterized by recurrent malignant ventricular arrhythmias in symptomatic cases, with left ventricular dysfunction serving as a key risk factor for sudden cardiac death.

Cite This Study

Stefan Peters (2007) studied this question.

synapsesocial.com/papers/6a7ffcb7377c56ad3031b7d2https://doi.org/10.2459/01.jcm.0000278450.35107.b3

Topics

Heart transplantationHeart failureHFrEF treatmentCardiac device therapy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Impairment in Arrhythmogenic Right Ventricular Dysplasia: What We Can Learn from Angiography2008 · 27 citations
  2. 2Right ventricular dysplasia: a report of 24 adult cases.1982 · 1,611 citations
  3. 3Predictors of adverse outcome in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy: long term experience of a tertiary care centre2005 · 121 citations
  4. 4Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy2000 · 339 citations
  5. 5Spectrum of Clinicopathologic Manifestations of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: A Multicenter Study1997 · 984 citations