Why the study?
Does the phase of the natural menstrual or oral contraceptive pill cycle attenuate the decline in popliteal artery endothelial function following a 3-hour bout of prolonged sitting in young females?
Does the phase of the natural menstrual or oral contraceptive pill cycle attenuate the decline in popliteal artery endothelial function following a 3-hour bout of prolonged sitting in young females?
Prolonged sitting causes a robust decline in popliteal artery endothelial function in young females, which is not attenuated by the phase of their natural menstrual or oral contraceptive pill cycle.
Sitting interruptions remain warranted across menstrual and OCP phases; challenges hypothesized hormonal protection and leaves open larger confirmatory studies.
We compared changes in popliteal artery endothelial function to a 3-h bout of sitting in females across their natural menstrual or oral contraceptive pill cycles. Pre-sitting endothelial-dependent vasodilation was greater in females who naturally menstruate during the later versus earlier phase but unchanged among contraceptive pill phases. Neither menstrual nor oral contraceptive pill phases attenuated the robust decline in conduit artery health following an acute period of uninterrupted sitting in young females.
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O’Brien et al. (2020) studied this question.
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