Population
Rats with chronic streptozotocin-induced diabetes maintained without treatment for 9-15 months
Comparison
Streptozotocin-induced diabetes (disease model) vs Control rats
Design
Preclinical
Follow-up
9-15 months
Authors
Loading...
Indicates selective dystrophic autonomic neuropathy without loss in diabetic rats; hypothesis-generating and requires human translation before clinical relevance.
Chronic streptozotocin-induced diabetes in rats leads to specific ultrastructural dystrophic changes and biochemical alterations in autonomic ganglia without significant neuronal loss.
Schmidt et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: