Why the study?
Does inhaled nitric oxide improve survival in patients with massive pulmonary embolism and acute right ventricular failure?
Population
4 patients with acute right ventricular failure secondary to massive near-fatal pulmonary embolism
Design
Case_series
Follow-up
to hospital discharge
Authors
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May support inhaled nitric oxide as temporizing therapy in massive PE; hypothesis-generating and requires prospective trials before practice change.
Does inhaled nitric oxide improve survival in patients with massive pulmonary embolism and acute right ventricular failure?
Inhaled nitric oxide may serve as an effective temporizing salvage therapy to decrease right ventricular afterload and support survival in massive pulmonary embolism.
Summerfield et al. (2012) studied this question.