Why the study?
Does statin therapy prevent stroke recurrence in patients who had a stroke or transient ischemic attack?
Does statin therapy prevent stroke recurrence in patients who had a stroke or transient ischemic attack?
This editorial discusses the SPARCL trial, which evaluated statin therapy for preventing stroke recurrence in patients with prior stroke or TIA.
Given the disparity in the numbers of cerebrovascular and cardiovascular clinical trials and the similarities in the interventions tested, it seems that stroke neurologists have had to peer at clinical-trial results over the shoulders of their cardiologist colleagues so often that they are at risk for chronic neck ailments. If only for evening the score a little, the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) investigators deserve our gratitude.In their randomized clinical trial that was specifically designed to test statin therapy for the prevention of stroke recurrence in patients who had had a stroke or transient ischemic . . .
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David M. Kent (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: