Why the study?
Catheter ablation for AF or left atrial tachycardia requires sedatives and analgesics to avoid pain and movement, but the safety of an EP staff-administered sedation protocol needed evaluation.
Is a sedation protocol with propofol, midazolam, and fentanyl administered by EP staff safe in patients undergoing left atrial ablation?
Population
3211 consecutive patients undergoing left atrial ablation for AF or left atrial tachycardia
Comparison
EP staff-administered sedation/anti-pain protocol with midazolam, fentanyl, and propofol
Design
Observational cohort study
Authors
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May support EP-staff deep sedation in high-volume labs with backup; leaves open generalizability and practice change.
Is a sedation protocol with propofol, midazolam, and fentanyl administered by EP staff safe in patients undergoing left atrial ablation?
Deep sedation with propofol, midazolam, and fentanyl administered by EP staff during left atrial ablation is safe, with a very low rate of respiratory interventions (1.53%), though patients with high BMI are at increased risk.
Foerschner et al. (2022) studied this question.
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