Key result
Unconscious sedation with propofol and midazolam during AF ablation was safe, with complications occurring in 2.5% of patients, none of which were attributable to the sedation itself.
Why the study?
Is unconscious sedation with intravenous propofol and midazolam safe and well-tolerated during catheter ablation of atrial fibrillation?
Cohort (n=316)
No
Is unconscious sedation with intravenous propofol and midazolam safe and well-tolerated during catheter ablation of atrial fibrillation?
Intravenous propofol and midazolam can be safely used for unconscious sedation during prolonged catheter ablation of atrial fibrillation without severe vital sign or electrolyte derangements.
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May support unconscious sedation in AF ablation; hypothesis-generating and requires randomized confirmation before practice change.
Wutzler et al. (2011) conducted a cohort in Symptomatic atrial fibrillation (n=316). Unconscious sedation with intravenous propofol and midazolam was evaluated on Complications during the procedure. Unconscious sedation with propofol and midazolam during AF ablation was safe, with complications occurring in 2.5% of patients, none of which were attributable to the sedation itself.
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