Why the study?
Do Tissue Doppler imaging (TDI) parameters and global function index (GFI) detect different degrees of regional myocardial dysfunction in various forms of hypertrophic cardiomyopathy compared to healthy controls?
Do Tissue Doppler imaging (TDI) parameters and global function index (GFI) detect different degrees of regional myocardial dysfunction in various forms of hypertrophic cardiomyopathy compared to healthy controls?
TDI parameters and GFI indicate regional systolic and diastolic myocardial dysfunction in all patients with HCM, regardless of the location of hypertrophy.
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May support GFI for detecting myocardial dysfunction across HCM phenotypes; hypothesis-generating pending prospective validation.
Saccheri et al. (2009) studied this question.
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